My last ten years of flying were on the B747-400, mainly pax but a small fleet, (8), of freighters.
Most relaxed time ever was on freighters. Just have to get used to the fact that no one really gives a toss about your transport etc. However, no one gives a toss if you get delayed or cause a delay.
Hard to beat Anchorage in the Spring/Summer/Autumn for a layover and probably the quickest de-icing station on the entire planet!
If I could have had the option to continue for a couple or three years on the freighters I would have jumped at it.