And despite the aircraft being certified for 1 pilot, your still flying over large stretches of water, scarce mountainous terrain with very changeable weather. Single pilot IFR in a 172 is challenging enough, so single pilot IFR while travelling in a jet in inclement weather would be tougher.
I've done the trip single pilot in SEP aircraft and also in King Airs.
It's a piece of cake in a King Air but takes a LOT more thought in a non de iced, unpressurised SEP.
My guess would be that it's even easier in a jet up above most of the weather