As far as "Wide-bodies" go, I'm assuming 767 or A330, or even perhaps 787 (down the track). Another Type, More dissimilar rated pilots/training/cycles, and simulators. Another set of spares inventories, more type ratings for engineers, more engineers?
I'm not saying it isn't possible, or even not necessary for that matter in order to compete with QF, but the money will have to come from somewhere. Where will the axe fall?