You are right about the ILS to the 13s... Which is why in 20 years operating out of that airport I have never shot an ILS in that direction...
Certain 22 approaches might conflict as well, hence the common use of VOR approaches, which take the final approach course off of the direct runway heading. Of course, it is quite possible that the choice of the VORs might ALSO have to do with noise rather than conflict or safety, it only takes one well connected person who to move the airplanes it seams these days.
Unless they have owned the house for 50 years or more, I am not sympathetic however.
Cheers
Wino