You land unpressurized.
Pilots wear O2 masks during arrival when cabin approaches 10,000' and from before engine start until cabin has descending below 10,000'(feels like it takes forever on departure
)
High ground speeds. Rotation is approx. 195 Kts
High alt switch to change altitudes for excessive cabin warning and for dropping O2 masks.
You walk slowly to deal with altitude issues.
Additional O2 bottles are available on the ground for passengers. Typically several get sick due to altitude adjustment issues. Never heard it being an issue for crew members(F/A's or pilots). Guess the the constant exposure to 5000'-7000'+ cabin cruise altitude helps.