Having now had 2 years of training/requalifying people in simulators I can perhaps offer a small piece of advice to just about every pilot out there (with the exception of the Edwards Air-Force Base Test Pilot that I had the privilege to train on type)...For the rest of you;
You're not as good as you think you are
You will screw up if too relaxed
You will screw up if too overloaded
When leaving the safety of the ground: Sit Up; Shut Up; Focus
When leaving the safety of altitude : Sit Up; Shut Up; Focus
I hope that helps