But even this was nothing compared to the initial usage of the Wright engine in WW2. The B29 was renowned for engine failures in the Pacific, it seems to have accounted for almost as many losses as enemy action.
Quite correct, my father flew B-29s and he told me that at max combat takeoff weight the loss of just one engine on takeoff would result in a crash, nearly all of which were fatal to all crew members. I'm trying to recall exactly how long after takeoff it was until the B-29 could be in a position to return for a safe landing after the loss of a engine. I think, and am willing to be corrected, that it was around three minutes and that required dumping the bomb load. He said basically that all takeoffs were 'ground effect' takeoffs before they knew what 'ground effect' was.
My father considered the B-29 horribly under powered. The B-50 was much better.