The question is still too broad........you need to nail down a few more variables.
Budget is, of course, the main factor. Purchase budget and running budget should both be considered. Where will you keep it? Five thousand feet of tarmac or 1000 feet of grass?
Add to this the need for extra training (initial and recurrent) because you will need an instrument rating to be able to do these trips in any sort of reliable fashion. Even with an IR you may still not make it every time unless you can afford an aircraft with decent ice protection. Passengers can be unforgiving when their ride is cancelled.
On a tight budget you could actually do well with a Comanche (please spell it properly). Forget 6 seats and you have room for 4 real adults plus baggage. The fuel options range from 60usg to 120usg and it will go for longer than most bladders can manage! But maintenance will require more effort on your part than something newer. Twin Com gives more warm fuzzies for long water legs with a family and deice possibilities.
Another option is a Cessna 210 - again forget the 6 seat options in favour of space and baggage.
But budget is the main consideration - does your pocket fit an old Cherokee 6 or a Malibu Mirage? Can you travel light in a C172 or take the kitchen sink in a Caravan?