The PPL training is critical, so pick your school and instructor well. Poor quality here will haunt you the whole way through and make it much harder to pass the IR flight skills test. People who have trouble with the IR are the ones who didn't learn proper trim technique and proper straight and level flight during PPL and CPL training.
A single FTO is less critical than you think, but use just one for the CPL, ME and IR. Recruiters won't care where you do the PPL and probably won't care how you did the hours building, but buzzing up and down the Florida beaches is not a good use of the time. Use it for proper navigation exercises and go to as many different places as you can. You can pick a different school for the ATPL theory. Again, recruiters won't care too much where you do it, just the results you achieve. There are schools that do nothing but theory and it's fine to use them. The school you choose for CPL. ME and IR might not offer MCC courses, so again, it's okay to go elsewhere for this last bit. Some people also do a JOC, but I would probably save that as a possible way to get some refresher sim hours in a cheaper block after a year or so if the job search drags on and on.
The most important thing of all is to find a very good PPL school so you get quality for the formative stage. Don't settle for a mediocre one because it is near home. Don't start it in the UK winter. Visit a dozen schools if you need to do so in order to start learning what a good one feels like and which ones are run by washed up used car salesmen. If you read enough on Pprune, you'll find the schools with the best reputations. Even if one of them isn't near you, reading about them will help you recognize a good one when you visit it.