I built myself a cockpit layout based on a Beechcraft Baron and it includes a yoke, rudder pedals, throttle quadrant, radio panel, switch panel and a few other bits and bobs. I use a top of the wozzer computer and monitor which give me a very good frame rate and graphics when using FSX Gold edition. Most of what I have come from Saitek and works very well.
By removing the yoke and throttle quadrant and hooking up my homemade collective and control stick, I have a fun helicopter simulator as well.
Total cost, excluding the PC and monitor, around 600quid.
Go and enjoy.