Wildpilot the C185 v C206 runs something like this.
Same engine much bigger/roomier/heavier cabin/aircraft in the 206.
C185 performs better than 206 in all respects.
C185 will lift more weight out of rough, marginal strips.
C206 easier to load - I have carried two 44 gallon drums in a C185 buts its a pain loading them and unloading.
C185 is a MUCH tougher aircraft - C206s tend to lose the odd nosegear. Yes 185s lose the odd tailwheel but the result is DRAMATICALLY less expensive.
Outside of niche markets - i.e. REAL bush flying - the C206 is probably the more economically viable aircraft.
While the 185 is undoubtedly a MUCH harder aeroplane than the 206 to fly well oddly enough it is MY view (shared by many I trained) that it was an easier aircraft to take in and out of short/rough/steep strips than a C206 once you knew how to fly them. C206s must be treated gently/are speed sensitive less you damage the firewall/rip out the nosegear - 185s you can just throw on the ground.