I do believe in having a 'cocktail' of progs to run at intervals
Only thing "cocktails" are good for is for slowing down your computer.
I never understand why people insist on running their computer as Administrator the whole time. Setup a new user, with limited privileges, and authenticate as administrator as and when you need to.
If you can't help your desire to run as Administrator, or need to because of some sloppy software programmer who can't write software properly then consider something like Faronics Deep Freeze that will set your computer back to a safe state after a quick reboot.