Argentina is a great place to fly. If heading for the winelands from Bs As, maintain heading 280 for 5.5 hours. You can stop enroute in San Luis for fuel if necessary. Scenery along the route is pretty dull, save for the Andes which you can see from miles away. There's an airfield in Mendoza (apart from SAME) near to Luján / Chacras de Coría that is better placed for visiting vinyards (which are at that end of the town). SAME has ILS if necessary. Mendoza is prone to a local wind known as "zonda", a hot wind which turns the sky orange with dirt and stones. Can't imagine it would be great for flying in so take local advice if you plan to fly around there.