You can fly with the absolute best (BA, Air France, AA etc etc) or you could fly with the perceived worst in the industry (Yemenia, All those ones on the euro black list etc etc) the point is THEY ALL CAN CRASH!
BA have had some scary situations the last few years, Air France...well they have a catalogue of disasters going back as far as the late 80s and well AA are just unfortunate but I suppose their size does sort of highlight the statistical aspect!
No matter how good the airline if something happens your time is up. Be more afraid of crossing the road or catching swine flu!!! I doubt you will end up being characterised in an episode of Air Crash Investigator just yet!