Well as with many things in life there's a down side and an up side.
It's a while since I have flown with the charter airlines and yes there is always the night flying/disruption factor etc.
BUT if you like flying it's VERY stimulating and challenging! Don't let anyone kid you that it's straightforward! You will be presented with a myriad of challenges, many of which have little to do with flying but much to do with CAPTAINCY!
Charter flying to all the usual destinations teaches you to think on you feet and make decisions whilst down the route.
If you want something that is going to stretch you and give you the ability to do almost any job in commercial aviation then go with the charter airlines.
Yes the "******ation" factor can be high but the job satisfaction can also be very high when you have to keep it altogether when you are on your third night flight towards the end of the season when you have a new FO with you going into CFU in the middle of a thunderstorm!
If you want a quiet life in the comfort zone then stay where you are but if you want to learn something new go to the charter companies. Enjoy!!