I think a LCY is possible but really there appears to be only VLM available to offer such a service, especially with the Air France KLM link and obvious onwards connections.
For the next 12 months, I feel DTV should be pushing out all the stops for the following;
JER 1 x weekly summer by FlyBE
BFS via IOM 2 x daily with Manx2.com (kills two bitds with one stone even with an NCL service)
DUB/ORK 1 or 2 x daily Aer Arann
LCY 2 x daily VLM
AGP/FAO/ALC/TFS/PMI summer timetable from one of the charters like TOM/TCX or even MON who could base a single 737 or A320. Obviously an EMB 190 sized aircraft would be better but I feel flyBE have committed to NCL/LBA for forseeable future even though they currently don't offer the med routes from these airports.
I cannot see anything more than the above being viable at MME but there should be no reason why the above services could not be successful.