I think most of us, both beancounters and aircrew, would agree that the only real problem is how much of that 570 tonnes is dead weight. It is a very heavy beast before you start adding fuel or payload, and the engines have to cary the dead weight before they start carrying payload.
That said, as others have already noted, it brings a whole new level of comfort (or in current configurations, legroom, at least) to the paying passenger. It remains to be seen how long it will take the beancounters to crib that extra leg room with extra seats to make the ca'ching! factor look more agreeable. Remember, the 74 started out with lounges and bars. They were soon replaced with closely packed seats. I don't think too many people would want to imagine (for example) what a two class EK 380 configured for DXB-BOM is going to look like.
Or a Jet* 380 configured for MEL-SYD.
Wait a few years and you won't have to imagine it.