IMHO - The "large" twins with wing mounted engines require the most aggressive use of controls in a crosswind takeoff/landing. Reason - the vertical stab is disproportionately large for the rest of the airframe, to keep the aircraft tracking straight with loss of engine at low speed/high thrust settings. They are powerefull weathervanes.
Along those lines....therefore the stresses involved in deflection/bending moments on the vertical stab are greater in these aircraft. It will be interesting to see how much of this type of analysis is included in the final report (way down the road) on AAL 587.