Let's forget the chromsome issues and focus instead on the person. Back in the 1970s I can remember flying with a steward who used to come to room parties dressed as a girl. He was a good steward and a nice person. I can remember him one evening explaining very lucidly the emotional difficulties of feeling female but trapped in a male body.
Several years later I climbed onto an aircraft leaving Heathrow and this attractive girl came up to me and said; "Hello, xxxx, do you remember me?" Of course, I didn't and then she told me who she had been.
I am glad to say that the company in its wisdom had decided to re-employ her after the operation. She was now a good stewardess, a good crew member and still a very nice person.
I have often thought of the enlightened manager who agreed to all this. I, also, hope that wherever she/he is she is happy and contented with her life.
Can I urge some who have written to PPRUNE to think a little more compassionately about the individual involved.