I'm in complete agreement with Rainboe, it is "far better to stick to discussing the question and what our experiences of it are".
I regularly fly the route mentioned in the original question, i.e. crossing Afghanistan / Pakistan.
Extended flight well above 10,000 feet is required, thus requiring an en-route Critical Point, with, as typical of any CP, onwards flight at or after the CP, and return if before.
For the route mentioned, if flying in a South-Easterly direction, return is made to Ashgabat UTAA (Turkmenistan) for depressurisation before the CP, or onwards flight to Lahore OPLA or Karachi OPKC if depressurisation at or after the CP.
Such flight requires carriage of considerably more oxygen than routinely required for "normal" depressurisation, and only about 50% of our aircraft carry the considerably increased (gaseous) oxygen supply.
For our entire global network, depressurisation strategies have been worked out, and routinely carried on all flights in paper form and the EFB.
Time gentleman please! Slanging match over..... nobody won, as usual.
Regards,
Old Smokey