Try reading this about Lycomings LOP:
http://www.avweb.com/articles/gamilycs.html
When I was running my TIO-541's LOP was not yet 'reinvented', but today I wouldn't hesitate to try LOP and watch the temperatures and smoothness. The JPI was not yet available then. TIT at 900°C or fuel flow (whichever was reached first) was the limiting factor for leaning , and the instrument needed calibration every year.
Porcorosso, since you are flying a twin, how about running one side LOP and the other ROP for a while, report what you find, including oil analysis.
Running LOP smoothly is also a very good indicator of the general health of your engine, induction leaks will show up quickly, marginal spark plugs, bad spark timing, etc. If an injector gets slightly clogged, that cylinder will run more lean (out of the danger zone) and the engine will run rough and let you know immediately. While ROP, a clogged injector can put the cylinder right in the danger zone without you ever knowing it.
If not yet equipped: this would be my priority: first get the JPI and learn to use it, then install GAMIjectors (if needed, maybe you have the perfect set of TCM injectors), then gather some data (JPI datalogging feature is perfect, download all temps to your PC and see the engine parameters for every 6 seconds of every flight from runup to shutdown).
Don't listen to OWT but make up your own mind, then you will have the option of running ROP or LOP when conditions require.