The F/O is HK based did not get a decent sleep for the last two nights and is completely stressed out. (Ie Divorce or what ever)
They have a technical problem in route (What ever) which stresses an elder CMD out, to the extent that he passes away as did a continental CMD recently.
Now you have a possibly low time experienced and completely fatigued / stressed out F/O in charge of a plane with a technical problem.
Lets hope he has plenty of fuel or the weather is gin clear in HK.
crewsunite, you forgot the one important detail that makes such a flight a non event. The all important computer flight plan!! With such a document you can show up for work in any state and the flight
will proceed as predicted according to the plan. Here says the CAD.