IMHO, the failure of IR1, IR2, IR3 and ISIS was at 02H11m. Jauh, If you're a pilot, you should know that, that is enough to turn an A330 (or any other heavy aircraft at night, in clouds and without a clue of what is going wrong with your aircraft), into a flying brick.
In those message reports there are warnings (WRN) and there are failures (FLR), and the above said components were allegedly failed on that report.
I also think that the Cabine pressure V/S advisory, means both CPC's were off and that message was a warning that Cabine Pressure could only be Manually Controlled.
To look for the reason (or reasons) of those failures is just another discussion, because for me, what this failures mean is that there is no reason to be discussing unreliable air speed indications once you have no ATTitude to grab to.
I must tell you that it is very disturbing to imagine the failure of all ADIRU plus ISIS. I never though this would be possible. Pitot and Static failures would only fail the ADR part of the ADIRU's, therefore one would still be capable of maintaining unreliable speed procedures (and attitude). There must have been something very disturbing and very grave to breack all of those components. Even the Emmergency Electrical Configuration status would leave you with one AP operational...