BA wouldn't be able to compete with LS, never mind FR and U2 out of MAN! They have too high a running cost. They only work effective out of large, slot capped airports such as LHR and it is the best place for them - as for major airline that fly as a major hub from one city within their country:
EY - AUH
AF - CDG/ORY
EK - DXB
QR - DOH
Probably more...