If you get offered something then grab it and don't let go.
Your family will need to understand any implications.
when I first started training for the ATPL, my wife said "I'll go anywhere except Northern Ireland"
After months of no flying job she said "I'll go anywhere but would rather not go to Northern Ireland"
I got my first job and we all spent a very happy 3 years in Northern Ireland.
Following on from GSXTY remarks about travelling time, I live in Southampton and rent a room at Stansted during the week. The room is 1.9miles from the airport. It takes me 25 minutes to get to the crew room from my crash pad. Previous to that I commuted 50 miles each way, round the M25 via Dartford Tunnel. I had to leave an absolute minimum of 1hr30 travelling time to get in, sometimes more. 3 hours travelling on top of a long day is not sustainable in the long term in my opinion.