Ditzy, it depends on the route. Routes through Afghanistan in the North/North East area have "escape" routes that would require the aircraft to remain well above 14,000' for much longer than that. The requirement for the Southern route may just be inside that, but if we are talking about JQ operating A332's to ATH & FCO then it is likely that they will fly routes through IRAN (despite the higher Air Navigation charges) & Turkey where the 22mins oxy will be sufficient.