Mexico City no problems - South side of runways for Gen Av.
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Barranquilla good size airport - has Gen Av as well, and customs/immigration.
Cartagena 70 KM W of BAQ, one of oldest city in Spanish Americas.
Santa Marta 80 KM E of BAQ. Nice beach resort city.
Barranquilla coastal area safest of Colombia.
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Manaus - suggested stop between Barranquilla and Rio,
Has customs/immigration. Look at alternate airports entire Amazon area.
Best hotel in Manaus is Tropical Resort Hotel. Great place.
Historic city (old opera) - Guided tours 1 or 2 days to native tribe villages.
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Rio, suggest Santos Dumont airport, for better Gen Av FBOs.
Hotels - suggest hotels at beach (1) Ipanema or (2) Copacabana.
Rio beach areas safe at night up to 4 or 5 blocks from beaches.
Scenic - is really worth a guided tour.
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Happy contrails