Manaus/Bogotá is a two and a half hour flight and part of it is over (very)high ground requiring contingency procedures for loss of pressurizaton/engine-out conditions. Besides the mountains there are always many thunderstorms making it even more complicate to be leveled at FL250-280 (what's the 1 engine out altitude capability?) Let's assume that such situation occurs during a take-off from an american field. Continuing ahead would probably be considered a violation and the pilots would have to face FAA/NTSB enforcement action. It appears that sometimes there are pilots that underestimate flying in this part of the world...
