A few incorrect things in the previous posts. A lot of airlines have P&W powered 757s. The 753 has higher thrust engines than the 752. A quick Google search gave the RB211 numbers 43.500 lbs as opposed to 40.200 for the 752.
As has happened with most aircraft being stretched, the wing did not change, power increase was modest, and the MTOW went up by 10 tons.
So inevitably, it needs more runway (higher speeds), climbs slower and the initial cruise altitude is 3-4000 feet lower at comparable load factor.
In some ways it is a dog, but it is economical on sectors up to 2000 nm, anything longer is not really worth it. Handles fine, but when you only fly it rarely, it lands a little bit earlier than little sister