I had three out last year and took a week off.
The effects of the drugs I was put on gave me motion sickness and light headedness at first. Not good for flying! Fine after a week though.
Also there is the effect of Boyle's law on the sockets to consider.
Pain not a problem compared to living with a cavity in a wisdom tooth for several months waiting for the op.
An added bonus was that the haemotologist gave me a right talking to before putting me on cyklokapron prior to the op, and I've been seven months off the smokes as a result!