I have used both AQD & Q-Pulse version 5 in the last couple of years. AQD is quite good and has a useful workbench tool. The Quality & Safety packages compliment one another. I think the latest version offers an FDM option. On the downside it is based on Microsoft Access & it doesn't work well in a Citrix environment.
Gael's Q-Pulse Version 5 is far better than previous versions for QMS. They have developed a bolt on package for Flight Safety reports, however I can't comment as I only so this whenwas still under development and have never used it.
In the dim & distant past I also used Winbasis which was developed by BA, but this appears to have been superceded by the above two.