I find that very hard to believe. I would classify the 747 and A380 as "really, really" large planes and their wings are protected. What is Lockheeds secret with the C5 ?!
Just do some research, you won't find it hard to believe. I believe the C-5 galaxy is in the size range of the whale and A380, but it is aerodynamically a much less complex aircraft. It doesn't even come close in cruise speed, and it is a completely different airfoil section designed more for higher lift at slower speeds and short field ops. I would hazard a guess that it is quite thicker in camber than the 74 and 380.
As to the A380 icing systems? I don't know what the A380 uses, not very familiar with its detailed systems. But I bet you they use wing AI even more infrequently than I do on the 400, if it even has such a system.