Best Altitude
All be it Beech Bonanza related, but a full chapter in John Eckelbars book, 'Flying The Beech Bonanza' is related to this very topic. A lot of trade offs with multiple factors affect the decision. He reckoned 4000' with the fuel injected IO-470-N was optimum. You also have to consider what it is you desire, economy/speed/weather/IFR-VFR etc.