DC-8
Four engines over water, period? That's what I thought when ETOPS hit the pilot lounge, and I reacted the same way. I was made to feel like a reactionary and dinosaur. But that was also when four engines meant four hot pipes, loud flow through a single orifice. What calms my psyche when I fly twins over the Pacific these days, is that I'm flying two hyper dependable propellor engines. Basically, (very basically) ducted thrust turbo-props. I'm still a prop guy at heart, so call me old fashioned.
I'm not so sure Al wouldn't have preferred to have been flying over water when #2 exploded over Sioux City. Forced landings are exceedingly rare.