FFF, as I'm flying the A320, which has many preprogrammed abnormal procedures, where we are required to push a button or two... I think an automated system could do that just as well. My experience however, also lies in abnormals which are not or are wrongly detected by the system.
How often we get a failure message where nothing is wrong, and sometimes we didn't get this message, where the smoke was pouring into the cockpit!
Maybe pilotless flight will be possible once, but it will take some time I guess, because IMHO the technique right now is not ready for it.