It depends where you are flying!
In Europe, you'd be most likely to use Navbox (which is what I use for trips all over).
In the USA, there are different packages - I'm not sure what the "preferred" one is these days but I'm sure there's someone around who knows.
For Africa, I don't know of any. My experience of Africa is one of trying to plan a trip, and giving up after finding that Avgas is rare and blokes with Kalashnikovs demanding money more frequent..