RB211 suffers a lot from disbonded attrition linings! I have no idea of the make-up of the v2500 but the 211 panels are in segments and were originally bonded in with 'Hysol' a very brittle adhesive that over time separated from the case in part due to flex. Also, holes in the septum layer cause corrosion of the honeycombe due to water ingress. We now use a 'thiokol' type material that is flexible to a degree and so at least the flexing factor is removed.
Disbond: Not a problem in itself (RB211) as long as there is no lifting. Depending on the amount of disbond and where on the panel it can be allowed to fly on for upto about 900hrs with regular inspections.
Panel loss: Usually causes a fan stall/surge due to the disturbed airflow and if unlucky will bend a couple of blades!