Aha... this old argument again!
Personally I use route up... but then I've always done a lot of walking, and that's the way I was taught. My instructor also taught me to fly that way.
I think the military teach you to fly north up, but they're not always right!
I annotate my route in the orientation I'll hold the map, so my notes are always easily readable.
I guess if you're going commercial it might be a different story though... so I'll leave the pros to it!
