Depending on the hours you ve flown, experience on type and a check out ride, I am sure it can be done.
Easiest is dry lease if you intend to fly quite a bit.
Old ones and those over-used (schools) may be the cheapest ones.
I ve rented out my Seneca IV before, but I am rather picky as to whom, because she s my baby and in pristine condition. I think you'll find most owners are like that.
You might be wiser to specify a little more what type of twin you are looking for, for which kind of sorties and what type of equipment you re looking for
Good luck!