Almost impossible to fly the 2500 on EPR as already explained due to small range of movement. Everyone I've spoken to flies it on N1.
Dont forget the potential inherent errors in any EPR indication (737 Potomac accident). Engine speed is the best indicator of real thrust.
Apart from that, the 2500 may be more fuel efficient but is a bit of a pain for the long start cycle, the slow response in levelling off and the EPR/N1 issue. However, they both work ans as long as they keep turning ....