For the 100/200 -
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The escape reels are of sufficient length to be used through the escape hatch onto the LH side
OR the RH side. There is very little difference in "length" passing the cable on either side. The hatch is offset (to the left) only by about 1 to 2 feet.
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It is possible to use the same reels for exit through the RH upper deck door (and optional LH upper deck door) on the 100/200 type airplanes, or even through the spiral staircase (passenger 100/200 types) or ladder (cargo upper deck types) to be used for egress through L-1
OR R-1 doors.
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In case of partial gear attitude (body gear NOT extended) it is possible that the length of the escape reel will not be sufficient to permit to reach the ground level, should the aircraft fall on the tail.
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On the 300 series, escape reels are usable through the escape hatch only.
Happy contrails