UK phraseology says that we have to stipulate the holding point when issuing a line up clearance.
i.e Bankcrupt Air,via Juliet 10,line and wait 25L.
It might have helped to prevent this.Also you can see quite clearly even on the 07's that they are lined up on the runway.If the ground radar was on this would easily be cross checked.
I'm shocked that this got 500m down a taxiway.That could be about 80kts.
The holes in the cheese lined up here.What about fatigue in the Tower controllers.After all CAD is telling them to do compulsory,unpaid overtime.