Well never say never. Rumours fly around from left right and centre but with Thomsons cutting back their flights from CWL there may be a possibility of a new operator to fill the gaps that Thomsons have left. Routes such as PMI, AGP, ALC etc. Will be interesting to see if any announcements are made in the next few months.
As for EZY and Continental, I would think it would be very unlikely (although I'm no expert). As these 2 airlines fly from BRS anyway, I wouldn't have thought they would fly from CWL as well