The noise profile is significantly different for pax between wing-mount and rear-fuselage-mount. The latter is a lot quieter.
But generally there are the stall problems of a high-T tail (the blanking effect of the engines on the tailplane in a high AOA), strengthening of the wings (and a leading edge design that smooths out the air flow to the engines and the tail in all configurations) that make it less attractive.
S.