I'm not familiar with the US regulations, Annex 14 and most ICAO signatory countries will permit an offset of 60cm on a runway (Annex 14, 5.3.12.5)and recommend no more than 30cm on a taxiway Annex 14, 5.3.16.11).
Ideally they should not be offset but it happens as taxiways/runways are widened or resurfaced (usually a cost savings measure, haven't heard of it being done on purpose for ease of painting, although it is one benefit).
bedder believeit, Can you point me to the relevant standard for requirement of blue lights at corners/intersections? As far as I know, blue edge lights are not required on taxiways equipped with centre line lighting (Annex 14, 5.3.17.1).