Less of a problem for you professional chappies who have librarians or whatever providing chart books for your aircraft but we humble amateurs (PPL/IR in my case) have to do our own updating and filing. Under the old format the page numbers were big and bold and in the top right hand corner of the page. Now the page number is in microscopic print in the top centre. Which means I definitely need my reading glasses, but worse I have to open each page almost completely to see the page number when searching for the page to replace. Net result will, I know, be an increase in the time spent updating the things.
And wouldn't it be most helpful if the update list said something like "Replace all" when say Amsterdam was being updated in it's entirety? Then I wouldn't have to go through each of the 50 odd individual pages checking whether it needed pulling and replacing....