However, I'm afraid on this occasion you have, like others here, failed to recognise that the gross risk related to the non-engine-failure-related hazards inherent in an extra landing and takeoff (the tech-stop) outweigh the reduction in risk gained by departing at less than MTOW.
Remember a US Navy DC-6 pilot many, many years ago getting a Bravo Zulu. Take off could be made (just - field limited) to destination and weather was such he couldn't return to the departure field if things went tits up. He elected only to load enough fuel to get him to an intermediate stop so making the take off a far less stressful event. You don't need me to tell you what happened immediately after reaching V1, having gotten some air another gave up the ghost under the strain. Some days..........