Wouldn't it be interesting if we just looked at how offshore do their avn ops, how corporate do it, how utility do it, etc. and draw the parallels and divergences, and go from there.
Having experienced all the above I can confidently make the assertion that distractions (usually from the medical side) and adrenalin (the rush rush rush syndrome, etc.) are the two MAJOR differences EMS pilots have to deal with. Another is thermal fatigue from all this silly safety crap we have to wear to be in accordance with that generated by standards organization/s that look only at, and mirror, military safety initiatives - nomex, helmets, gloves, high-top leather boots, etc. etc. etc. I support it, when the weather is amenable to its use, but when the weather gets warm we are adding a type of distraction, thermal fatigue aka increase in body core temp, that IS fixable by shedding this stuff, and quickly.