It depends on the situation... e.g. a relitively simple departure, visual day, then depending upon the captain I'll happily hand fly it, although it tends to get dull above 20K. It's good if you can practice at least one level off though...
As for arrivals, if a visual approach, downwind or base, when the automatics are of no longer any use. Flying takes up so much capacity that it is difficult to make the most efficient approach while hand flying...