I'll take a lot of convincing that it is safer to hand fly a non-ILS approach in a big jet.
I don't mean build the fanciest looking map, but simply use (on B744) the rwy c/line display to aid your tracking if there in no ILS in the data base. Then use the A/P in HDG SEL and V/S modes. Now you have another "pilot" you can rely on flying the A/C while you monitor and think. You may be lucky and have a suitably coded approach in the data base to give you LNav and VNav. Either way, A/P is the safe way.